Varaico: Literature-Extracted Genetic Variants

TTF2

1,233 papers

RefSeq Summary

This gene encodes a member of the SWI2/SNF2 family of proteins, which play a critical role in altering protein-DNA interactions. The encoded protein has been shown to have dsDNA-dependent ATPase activ...

Pfam Domains

Zn_ribbon_GRFaa 4–42UCSCGRF zinc finger

SNF2-rel_domaa 573–932UCSCSNF2-related domain

Helicase_Caa 991–1106UCSCHelicase conserved C-terminal domain

Gene Aliases

HGNC Name

transcription termination factor 2

HGNC Alias Symbols

HuF2; ZGRF6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003594.4

p.K27K

c.81G>A

Surrounding Variants

2 papers

NM_003594.4

p.K27R

c.80A>G

1 paper

NM_003594.4

p.S28G

c.82A>G

1 paper

NM_003594.4

p.G26G

c.78A>G

1 paper

NM_003594.4

p.S28R

c.84C>A

1 paper

NM_003594.4

p.G26E

c.77G>A

1 paper

NM_003594.4

p.K27insFs

c.79_80insA

1 paper

NM_003594.4

p.F29I

c.85T>A

1 paper

NM_003594.4

p.K25K

c.75A>G

1 paper

NM_003594.4

p.K25insFs

c.74_75insG

1 paper

NM_003594.4

p.K25I

c.74A>T

1 paper

NM_003594.4

p.Y30H

c.88T>C

1 paper

NM_003594.4

p.K25E

c.73A>G