Varaico: Literature-Extracted Genetic Variants

TTF2

1,233 papers

RefSeq Summary

This gene encodes a member of the SWI2/SNF2 family of proteins, which play a critical role in altering protein-DNA interactions. The encoded protein has been shown to have dsDNA-dependent ATPase activ...

Pfam Domains

Zn_ribbon_GRFaa 4–42UCSCGRF zinc finger

SNF2-rel_domaa 573–932UCSCSNF2-related domain

Helicase_Caa 991–1106UCSCHelicase conserved C-terminal domain

Gene Aliases

HGNC Name

transcription termination factor 2

HGNC Alias Symbols

HuF2; ZGRF6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003594.4

p.L955P

c.2864T>C

Surrounding Variants

2 papers

NM_003594.4

p.S956G

c.2866A>G

1 paper

NM_003594.4

p.S956N

c.2867G>A

4 papers

NM_003594.4

p.E952K

c.2854G>A

1 paper

NM_003594.4

p.L958F

c.2874G>C

1 paper

NM_003594.4

p.L958F

c.2874G>T

1 paper

NM_003594.4

p.L951L

c.2851C>T

1 paper

NM_003594.4

p.V948V

c.2844C>T

1 paper

NM_003594.4

p.L974L

c.2922T>C

1 paper

NM_003594.4

p.G976S

c.2926G>A

1 paper

NM_003594.4

p.G986D

c.2957G>A

1 paper

NM_003594.4

p.G986A

c.2957G>C

1 paper

NM_003594.4

p.E989G

c.2966A>G