Varaico: Literature-Extracted Genetic Variants

Gene:TUBB2A
Variant:p.E421D

TUBB2A

173 papers

RefSeq Summary

Microtubules, key participants in processes such as mitosis and intracellular transport, are composed of heterodimers of alpha- and beta-tubulins. The protein encoded by this gene is a beta-tubulin. D...

Pfam Domains

Tubulinaa 3–212UCSCTubulin/FtsZ family, GTPase domain
Tubulin_Caa 261–383UCSCTubulin C-terminal domain

Gene Aliases

HGNC Name

tubulin beta 2A class IIa

HGNC Previous Symbol

TUBB2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001069.3
p.E421D
c.1263G>C
Surrounding Variants
1 paper
NM_001069.3
p.E421D
c.1263G>T
2 papers
NM_001069.3
p.E421K
c.1261G>A
1 paper
NM_001069.3
p.V419_S420insFs
c.1255_1258dup4
1 paper
NM_001069.3
p.D417_V419delFs
c.1251_1255del5
1 paper
NM_001069.3
p.D417H
c.1249G>C
10 papers
NM_001069.3
p.D417N
c.1249G>A
1 paper
NM_001069.3
p.M415I
c.1245G>A
1 paper
NM_001069.3
p.E412K
c.1234G>A
4 papers
NM_001069.3
p.E410K
c.1228G>A
1 paper
NM_001069.3
p.E437K
c.1309G>A
1 paper
NM_001069.3
p.G402V
c.1205G>T
1 paper
NM_001069.3
p.G402D
c.1205G>A
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