Varaico: Literature-Extracted Genetic Variants

TUBB2B

217 papers

RefSeq Summary

The protein encoded by this gene is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. This gene is highly similar to TUBB2A and TUBB2C. Defects in this gene are a ca...

Pfam Domains

Tubulinaa 3–212UCSCTubulin/FtsZ family, GTPase domain

Tubulin_Caa 261–383UCSCTubulin C-terminal domain

Gene Aliases

HGNC Name

tubulin beta 2B class IIb

HGNC Alias Symbols

MGC8685; DKFZp566F223; bA506K6.1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_178012.5

p.G360_K362Fs

c.1080_1084delinsACATCTFs

Surrounding Variants

2 papers

NM_178012.5

p.G360_K362delins

c.1080_1084delinsACATCTTC

2 papers

NM_178012.5

p.G360_K362delFs

c.1080_1084del5

1 paper

NM_178012.5

p.L361fs

c.1081_1082fs

1 paper

NM_178012.5

p.M363T

c.1088T>C

1 paper

NM_178012.5

p.S364A

c.1090T>G

1 paper

NM_178012.5

p.P358L

c.1073C>T

1 paper

NM_178012.5

p.P358T

c.1072C>A

5 papers

NM_178012.5

p.P357L

c.1070C>T

1 paper

NM_178012.5

p.I356T

c.1067T>C

1 paper

NM_178012.5

p.G369S

c.1105G>A

1 paper

NM_178012.5

p.D355N

c.1063G>A

2 papers

NM_178012.5

p.G369V

c.1106G>T