Varaico: Literature-Extracted Genetic Variants

TUBB2B

217 papers

RefSeq Summary

The protein encoded by this gene is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. This gene is highly similar to TUBB2A and TUBB2C. Defects in this gene are a ca...

Pfam Domains

Tubulinaa 3–212UCSCTubulin/FtsZ family, GTPase domain

Tubulin_Caa 261–383UCSCTubulin C-terminal domain

Gene Aliases

HGNC Name

tubulin beta 2B class IIb

HGNC Alias Symbols

MGC8685; DKFZp566F223; bA506K6.1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

9 papers

NM_178012.5

p.T312M

c.935C>T

Surrounding Variants

1 paper

NM_178012.5

p.R309G

c.925C>G

1 paper

NM_178012.5

p.R318W

c.952C>T

1 paper

NM_178012.5

p.V313_F317del5

c.937_950del15

1 paper

NM_178012.5

p.R306C

c.916C>T

1 paper

NM_178012.5

p.R320C

c.958C>T

1 paper

NM_178012.5

p.R320H

c.959G>A

1 paper

NM_178012.5

p.C303S

c.908G>C

1 paper

NM_178012.5

p.C303Y

c.908G>A

1 paper

NM_178012.5

p.C303S

c.907T>A

4 papers

NM_178012.5

p.A302V

c.905C>T

1 paper

NM_178012.5

p.A302S

c.904G>T

4 papers

NM_178012.5

p.A302T

c.904G>A