Varaico: Literature-Extracted Genetic Variants

TUBB2B

217 papers

RefSeq Summary

The protein encoded by this gene is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. This gene is highly similar to TUBB2A and TUBB2C. Defects in this gene are a ca...

Pfam Domains

Tubulinaa 3–212UCSCTubulin/FtsZ family, GTPase domain

Tubulin_Caa 261–383UCSCTubulin C-terminal domain

Gene Aliases

HGNC Name

tubulin beta 2B class IIb

HGNC Alias Symbols

MGC8685; DKFZp566F223; bA506K6.1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_178012.5

p.Q291K

c.871C>A

Surrounding Variants

1 paper

NM_178012.5

p.Q291R

c.872A>G

1 paper

NM_178012.5

p.Q291P

c.872A>C

1 paper

NM_178012.5

p.T290I

c.869C>T

2 papers

NM_178012.5

p.Q292E

c.874C>G

1 paper

NM_178012.5

p.Q292K

c.874C>A

1 paper

NM_178012.5

p.E288G

c.863A>G

5 papers

NM_178012.5

p.E288K

c.862G>A

1 paper

NM_178012.5

p.P287L

c.860C>T

6 papers

NM_178012.5

p.M299V

c.895A>G

1 paper

NM_178012.5

p.M299L

c.895A>C

1 paper

NM_178012.5

p.M299I

c.897G>T

1 paper

NM_178012.5

p.M299I

c.897G>C