Varaico: Literature-Extracted Genetic Variants

TUBB2B

217 papers

RefSeq Summary

The protein encoded by this gene is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. This gene is highly similar to TUBB2A and TUBB2C. Defects in this gene are a ca...

Pfam Domains

Tubulinaa 3–212UCSCTubulin/FtsZ family, GTPase domain

Tubulin_Caa 261–383UCSCTubulin C-terminal domain

Gene Aliases

HGNC Name

tubulin beta 2B class IIb

HGNC Alias Symbols

MGC8685; DKFZp566F223; bA506K6.1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

16 papers

NM_178012.5

p.F265L

c.793T>C

Surrounding Variants

15 papers

NM_178012.5

p.F265L

c.795C>G

15 papers

NM_178012.5

p.F265L

c.795C>A

2 papers

NM_178012.5

p.H264Y

c.790C>T

1 paper

NM_178012.5

p.L263L

c.789G>A

2 papers

NM_178012.5

p.L263M

c.787C>A

3 papers

NM_178012.5

p.M267V

c.799A>G

5 papers

NM_178012.5

p.R262H

c.785G>A

5 papers

NM_178012.5

p.R262C

c.784C>T

1 paper

NM_178012.5

p.F270C

c.809T>G

1 paper

NM_178012.5

p.F270Y

c.809T>A

1 paper

NM_178012.5

p.P259L

c.776C>T

1 paper

NM_178012.5

p.A271T

c.811G>A