Varaico: Literature-Extracted Genetic Variants

Gene:TUBB8
Variant:p.N89Y

TUBB8

159 papers

RefSeq Summary

The protein encoded by this gene represents the primary beta-tubulin subunit of oocytes and the early embryo. Defects in this gene, which is primate-specific, are a cause of oocyte maturation defect 2...

Pfam Domains

Tubulinaa 3–212UCSCTubulin/FtsZ family, GTPase domain
Tubulin_Caa 261–383UCSCTubulin C-terminal domain

Gene Aliases

HGNC Name

tubulin beta 8 class VIII

HGNC Alias Symbol

bA631M21.2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_177987.3
p.N89Y
c.265A>T
Surrounding Variants
1 paper
NM_177987.3
p.N89K
c.267C>G
1 paper
NM_177987.3
p.N89K
c.267C>A
3 papers
NM_177987.3
p.D88H
c.262G>C
1 paper
NM_177987.3
p.D88N
c.262G>A
5 papers
NM_177987.3
p.P87L
c.260C>T
4 papers
NM_177987.3
p.F90insFs
c.269dupT
3 papers
NM_177987.3
p.I91fs
c.271_272fs
1 paper
NM_177987.3
p.F85L
c.255C>G
1 paper
NM_177987.3
p.F85L
c.255C>A
1 paper
NM_177987.3
p.F85L
c.253T>C
1 paper
NM_177987.3
p.G93S
c.277G>A
1 paper
NM_177987.3
p.Q83L
c.248A>T
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