thioredoxin domain containing 12

TLP19

ERP18

ERP19

hAG-1

AGR1

PDIA16

thioredoxin domain containing 12 (endoplasmic reticulum)

endoplasmic reticulum thioredoxin superfamily member, 18 kDa

anterior gradient homolog 1 (Xenopus laevis)

protein disulfide isomerase family A, member 16

Thioredoxin domain-containing protein 12

Endoplasmic reticulum resident protein 18

Endoplasmic reticulum resident protein 19

Thioredoxin-like protein p19

hTLP19

ER protein 18

ERp18

ER protein 19

ERp19

This gene encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. This protein localizes to the endoplasmic reticulum and has a single atypical active motif. The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases. This protein may play a role in defense against endoplasmic reticulum stress. Alternate splicing results in both coding and non-coding variants. [provided by RefSeq, Mar 2012].

Varaico: Literature-Extracted Genetic Variants

TXNDC12

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Alias Symbols