Varaico: Literature-Extracted Genetic Variants

TXNRD2

209 papers

RefSeq Summary

The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are fo...

Pfam Domains

Pyr_redox_2aa 40–375UCSCPyridine nucleotide-disulphide oxidoreductase

Pyr_redox_dimaa 395–508UCSCPyridine nucleotide-disulphide oxidoreductase, dimerisation domain

Gene Aliases

HGNC Name

thioredoxin reductase 2

HGNC Alias Symbols

TR; TRXR2; TR3; SELZ; TXNR2

Papers

RefSeq ID

Protein change

DNA change

1–12 of 244 variants

18 papers

NM_006440.5

p.Y447*

c.1341T>G

16 papers

NM_006440.5

p.Y447*

c.1341T>A

15 papers

NM_006440.5

p.A66S

c.196G>T

8 papers

NM_006440.5

p.I370T

c.1109T>C

7 papers

NM_006440.5

p.S299R

c.895A>C

7 papers

NM_006440.5

p.S299R

c.897C>G

7 papers

NM_006440.5

p.S299R

c.897C>A

6 papers

NM_006440.5

p.A59T

c.175G>A

6 papers

NM_006440.5

p.A234T

c.700G>A

6 papers

NM_006440.5

p.G375R

c.1123G>C

6 papers

NM_006440.5

p.G375R

c.1123G>A

5 papers

NM_006440.5

p.V361M

c.1081G>A