Varaico: Literature-Extracted Genetic Variants

TXNRD2

209 papers

RefSeq Summary

The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are fo...

Pfam Domains

Pyr_redox_2aa 40–375UCSCPyridine nucleotide-disulphide oxidoreductase

Pyr_redox_dimaa 395–508UCSCPyridine nucleotide-disulphide oxidoreductase, dimerisation domain

Gene Aliases

HGNC Name

thioredoxin reductase 2

HGNC Alias Symbols

TR; TRXR2; TR3; SELZ; TXNR2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006440.5

p.D388A

c.1163A>C

Surrounding Variants

1 paper

NM_006440.5

p.M390R

c.1169T>G

2 papers

NM_006440.5

p.S386F

c.1157C>T

1 paper

NM_006440.5

p.S386A

c.1156T>G

1 paper

NM_006440.5

p.G385E

c.1154G>A

4 papers

NM_006440.5

p.G384S

c.1150G>A

1 paper

NM_006440.5

p.N394K

c.1182T>G

1 paper

NM_006440.5

p.N394K

c.1182T>A

1 paper

NM_006440.5

p.R381W

c.1141C>T

1 paper

NM_006440.5

p.V379V

c.1137G>A

1 paper

NM_006440.5

p.N394_V395Splc

c.1182+19C>T

3 papers

NM_006440.5

p.G375E

c.1124G>A

1 paper

NM_006440.5

p.N394_V395Splc

c.1182+20G>A