Varaico: Literature-Extracted Genetic Variants

TXNRD2

209 papers

RefSeq Summary

The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are fo...

Pfam Domains

Pyr_redox_2aa 40–375UCSCPyridine nucleotide-disulphide oxidoreductase

Pyr_redox_dimaa 395–508UCSCPyridine nucleotide-disulphide oxidoreductase, dimerisation domain

Gene Aliases

HGNC Name

thioredoxin reductase 2

HGNC Alias Symbols

TR; TRXR2; TR3; SELZ; TXNR2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006440.5

p.E362_G363Splc

c.1087-8T>C

Surrounding Variants

1 paper

NM_006440.5

p.E362_G363Splc

c.1087-11C>T

1 paper

NM_006440.5

p.G363E

c.1088G>A

1 paper

NM_006440.5

p.R364Q

c.1091G>A

1 paper

NM_006440.5

p.L367L

c.1101G>A

8 papers

NM_006440.5

p.I370T

c.1109T>C

1 paper

NM_006440.5

p.M373V

c.1117A>G

1 paper

NM_006440.5

p.M373T

c.1118T>C

6 papers

NM_006440.5

p.G375R

c.1123G>C

6 papers

NM_006440.5

p.G375R

c.1123G>A

3 papers

NM_006440.5

p.G375E

c.1124G>A

1 paper

NM_006440.5

p.V379V

c.1137G>A

1 paper

NM_006440.5

p.R381W

c.1141C>T