Varaico: Literature-Extracted Genetic Variants

TXNRD2

209 papers

RefSeq Summary

The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are fo...

Pfam Domains

Pyr_redox_2aa 40–375UCSCPyridine nucleotide-disulphide oxidoreductase

Pyr_redox_dimaa 395–508UCSCPyridine nucleotide-disulphide oxidoreductase, dimerisation domain

Gene Aliases

HGNC Name

thioredoxin reductase 2

HGNC Alias Symbols

TR; TRXR2; TR3; SELZ; TXNR2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006440.5

p.D359D

c.1077C>T

Surrounding Variants

5 papers

NM_006440.5

p.V361M

c.1081G>A

1 paper

NM_006440.5

p.E362A

c.1085A>C

1 paper

NM_006440.5

p.A356V

c.1067C>T

2 papers

NM_006440.5

p.P352T

c.1054C>A

1 paper

NM_006440.5

p.S350P

c.1048T>C

1 paper

NM_006440.5

p.E347Q

c.1039G>C

1 paper

NM_006440.5

p.R346Q

c.1037G>A

1 paper

NM_006440.5

p.L342P

c.1025T>C

1 paper

NM_006440.5

p.L342V

c.1024C>G

1 paper

NM_006440.5

p.I341N

c.1022T>A

2 papers

NM_006440.5

p.L325insFs

c.973dupC

1 paper

NM_006440.5

p.R323K

c.968G>A