Varaico: Literature-Extracted Genetic Variants

TXNRD2

209 papers

RefSeq Summary

The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are fo...

Pfam Domains

Pyr_redox_2aa 40–375UCSCPyridine nucleotide-disulphide oxidoreductase

Pyr_redox_dimaa 395–508UCSCPyridine nucleotide-disulphide oxidoreductase, dimerisation domain

Gene Aliases

HGNC Name

thioredoxin reductase 2

HGNC Alias Symbols

TR; TRXR2; TR3; SELZ; TXNR2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006440.5

p.L287V

c.859C>G

Surrounding Variants

2 papers

NM_006440.5

p.R286S

c.858G>T

2 papers

NM_006440.5

p.R286S

c.858G>C

1 paper

NM_006440.5

p.D289N

c.865G>A

1 paper

NM_006440.5

p.D289V

c.866A>T

1 paper

NM_006440.5

p.V284insFs

c.850_851insA

1 paper

NM_006440.5

p.G290V

c.869G>T

1 paper

NM_006440.5

p.A280T

c.838G>A

1 paper

NM_006440.5

p.G278G

c.834C>A

7 papers

NM_006440.5

p.S299R

c.895A>C

1 paper

NM_006440.5

p.S299N

c.896G>A

7 papers

NM_006440.5

p.S299R

c.897C>G

7 papers

NM_006440.5

p.S299R

c.897C>A