Varaico: Literature-Extracted Genetic Variants

TXNRD2

209 papers

RefSeq Summary

The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are fo...

Pfam Domains

Pyr_redox_2aa 40–375UCSCPyridine nucleotide-disulphide oxidoreductase

Pyr_redox_dimaa 395–508UCSCPyridine nucleotide-disulphide oxidoreductase, dimerisation domain

Gene Aliases

HGNC Name

thioredoxin reductase 2

HGNC Alias Symbols

TR; TRXR2; TR3; SELZ; TXNR2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006440.5

p.M263I

c.789G>C

Surrounding Variants

1 paper

NM_006440.5

p.M263K

c.788T>A

1 paper

NM_006440.5

p.V264I

c.790G>A

1 paper

NM_006440.5

p.V264A

c.791T>C

2 papers

NM_006440.5

p.V264D

c.791T>A

1 paper

NM_006440.5

p.H271D

c.811C>G

2 papers

NM_006440.5

p.G272G

c.816C>T

1 paper

NM_006440.5

p.T273T

c.819C>T

1 paper

NM_006440.5

p.R274W

c.820C>T

1 paper

NM_006440.5

p.Q258_Q259Splc

c.775-19G>A

1 paper

NM_006440.5

p.G278G

c.834C>A

1 paper

NM_006440.5

p.A280T

c.838G>A

1 paper

NM_006440.5

p.V284insFs

c.850_851insA