Varaico: Literature-Extracted Genetic Variants

TXNRD2

209 papers

RefSeq Summary

The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are fo...

Pfam Domains

Pyr_redox_2aa 40–375UCSCPyridine nucleotide-disulphide oxidoreductase

Pyr_redox_dimaa 395–508UCSCPyridine nucleotide-disulphide oxidoreductase, dimerisation domain

Gene Aliases

HGNC Name

thioredoxin reductase 2

HGNC Alias Symbols

TR; TRXR2; TR3; SELZ; TXNR2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006440.5

p.L242L

c.724C>T

Surrounding Variants

1 paper

NM_006440.5

p.L242L

c.726G>A

2 papers

NM_006440.5

p.G239R

c.715G>A

1 paper

NM_006440.5

p.I246I

c.738C>T

1 paper

NM_006440.5

p.I246_M247insFs

c.738_739ins7

1 paper

NM_006440.5

p.G235D

c.704G>A

1 paper

NM_006440.5

p.M247_M248delFs

c.739_743del5

2 papers

NM_006440.5

p.R249C

c.745C>T

2 papers

NM_006440.5

p.A234V

c.701C>T

2 papers

NM_006440.5

p.A234D

c.701C>A

6 papers

NM_006440.5

p.A234T

c.700G>A

1 paper

NM_006440.5

p.L231L

c.691C>T

1 paper

NM_006440.5

p.R254C

c.760C>T