Varaico: Literature-Extracted Genetic Variants

TXNRD2

209 papers

RefSeq Summary

The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are fo...

Pfam Domains

Pyr_redox_2aa 40–375UCSCPyridine nucleotide-disulphide oxidoreductase

Pyr_redox_dimaa 395–508UCSCPyridine nucleotide-disulphide oxidoreductase, dimerisation domain

Gene Aliases

HGNC Name

thioredoxin reductase 2

HGNC Alias Symbols

TR; TRXR2; TR3; SELZ; TXNR2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006440.5

p.D69E

c.207C>A

Surrounding Variants

1 paper

NM_006440.5

p.D69E

c.207C>G

1 paper

NM_006440.5

p.Y70_V71insG

c.208_212ins3

1 paper

NM_006440.5

p.D69N

c.205G>A

1 paper

NM_006440.5

p.Y70Y

c.210C>T

1 paper

NM_006440.5

p.V68_E72delFs

c.204_214del11

15 papers

NM_006440.5

p.A66S

c.196G>T

1 paper

NM_006440.5

p.R63delFs

c.189delC

1 paper

NM_006440.5

p.A59A

c.177C>T

2 papers

NM_006440.5

p.A59V

c.176C>T

1 paper

NM_006440.5

p.A59P

c.175G>C

6 papers

NM_006440.5

p.A59T

c.175G>A

1 paper

NM_006440.5

p.G77Splc

c.229+15A>G