Varaico: Literature-Extracted Genetic Variants

TXNRD3

97 papers

RefSeq Summary

The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are fo...

Pfam Domains

Glutaredoxinaa 68–130UCSCGlutaredoxin

Pyr_redox_2aa 157–494UCSCPyridine nucleotide-disulphide oxidoreductase

Pyr_redox_dimaa 514–627UCSCPyridine nucleotide-disulphide oxidoreductase, dimerisation domain

Gene Aliases

HGNC Name

thioredoxin reductase 3

HGNC Previous Symbols

TXNRD3NB; TXNRD3IT1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_052883.3

p.P45T

c.133C>A

Surrounding Variants

1 paper

NM_052883.3

p.S49A

c.145T>G

1 paper

NM_052883.3

p.R52C

c.154C>T

1 paper

NM_052883.3

p.P34L

c.101C>T

1 paper

NM_052883.3

p.L31L

c.93G>A

1 paper

NM_052883.3

p.L59L

c.177C>T

1 paper

NM_052883.3

p.L62insFs

c.185_186insA

1 paper

NM_052883.3

p.G27insFs

c.80_81insT

1 paper

NM_052883.3

p.R26P

c.77G>C

1 paper

NM_052883.3

p.I63I

c.189C>A

2 papers

NM_052883.3

p.R26fs

c.76_77fs

1 paper

NM_052883.3

p.V25I

c.73G>A

1 paper

NM_052883.3

p.S22W

c.65C>G