Varaico: Literature-Extracted Genetic Variants

Gene:TYMS
Variant:p.L8L

TYMS

448 papers

RefSeq Summary

Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using, 10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-pr...

Pfam Domains

Thymidylat_syntaa 31–313UCSCThymidylate synthase

Gene Aliases

HGNC Name

thymidylate synthetase

HGNC Previous Symbol

TS

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001071.4
p.L8L
c.24G>A
Surrounding Variants
2 papers
NM_001071.4
p.L8Q
c.23T>A
1 paper
NM_001071.4
p.L8delFs
c.23delT
1 paper
NM_001071.4
p.E7E
c.21G>A
1 paper
NM_001071.4
p.R10G
c.28C>G
1 paper
NM_001071.4
p.R10R
c.30C>A
1 paper
NM_001071.4
p.S6S
c.18G>C
2 papers
NM_001071.4
p.P12A
c.34C>G
3 papers
NM_001071.4
p.G5D
c.14G>A
1 paper
NM_001071.4
p.P12_L13ins2
c.36_37ins6
3 papers
NM_001071.4
p.P12L
c.35C>T
4 papers
NM_001071.4
p.G5S
c.13G>A
3 papers
NM_001071.4
p.G5R
c.13G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."