Varaico: Literature-Extracted Genetic Variants

Gene:TYMS
Variant:p.I178_M179insFs

TYMS

448 papers

RefSeq Summary

Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using, 10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-pr...

Pfam Domains

Thymidylat_syntaa 31–313UCSCThymidylate synthase

Gene Aliases

HGNC Name

thymidylate synthetase

HGNC Previous Symbol

TS

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_001071.4
p.I178_M179insFs
c.534_535insTG
Surrounding Variants
1 paper
NM_001071.4
p.I178V
c.532A>G
1 paper
NM_001071.4
p.C180S
c.538T>A
1 paper
NM_001071.4
p.C180S
c.539G>C
1 paper
NM_001071.4
p.R176R
c.528A>G
1 paper
NM_001071.4
p.I177del1
c.529_531delATC
2 papers
NM_001071.4
p.R176K
c.527G>A
1 paper
NM_001071.4
p.A181T
c.541G>A
1 paper
NM_001071.4
p.R175K
c.524G>A
1 paper
NM_001071.4
p.R175G
c.523A>G
1 paper
NM_001071.4
p.N183S
c.548A>G
1 paper
NM_001071.4
p.P184P
c.552A>C
3 papers
NM_001071.4
p.R185G
c.553A>G
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