Varaico: Literature-Extracted Genetic Variants

TYRO3

184 papers

RefSeq Summary

The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-...

Pfam Domains

I-setaa 43–135UCSCImmunoglobulin I-set domain

fn3aa 226–316UCSCFibronectin type III domain

fn3aa 324–412UCSCFibronectin type III domain

PK_Tyr_Ser-Thraa 518–786UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

TYRO3 protein tyrosine kinase

HGNC Previous Symbol

RSE

Papers

RefSeq ID

Protein change

DNA change

1–12 of 250 variants

7 papers

NM_006293.4

p.V669L

c.2005G>C

7 papers

NM_006293.4

p.V669L

c.2005G>T

6 papers

NM_006293.4

p.I346N

c.1037T>A

6 papers

NM_006293.4

p.L495Splc

c.1484-1G>T

4 papers

NM_006293.4

p.E489K

c.1465G>A

3 papers

NM_006293.4

p.G418Splc

c.1252+2T>C

3 papers

NM_006293.4

p.R687C

c.2059C>T

2 papers

NM_006293.4

p.M1insFs

c.1_2ins26

2 papers

NM_006293.4

p.L23L

c.69C>T

2 papers

NM_006293.4

p.A29_E37del0

c.86_109del24

2 papers

NM_006293.4

p.A223fs

c.667_668fs

2 papers

NM_006293.4

p.P314L

c.941C>T