Varaico: Literature-Extracted Genetic Variants

TYRO3

184 papers

RefSeq Summary

The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-...

Pfam Domains

I-setaa 43–135UCSCImmunoglobulin I-set domain

fn3aa 226–316UCSCFibronectin type III domain

fn3aa 324–412UCSCFibronectin type III domain

PK_Tyr_Ser-Thraa 518–786UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

TYRO3 protein tyrosine kinase

HGNC Previous Symbol

RSE

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_006293.4

p.I346N

c.1037T>A

Surrounding Variants

1 paper

NM_006293.4

p.P347S

c.1039C>T

1 paper

NM_006293.4

p.P347fs

c.1039_1040fs

1 paper

NM_006293.4

p.E348fs

c.1042_1043fs

1 paper

NM_006293.4

p.E348_E352delFs

c.1043_1055del13

1 paper

NM_006293.4

p.G353S

c.1057G>A

1 paper

NM_006293.4

p.D335N

c.1003G>A

1 paper

NM_006293.4

p.R333H

c.998G>A

1 paper

NM_006293.4

p.Q327L

c.980A>T

1 paper

NM_006293.4

p.A323fs

c.967_968fs

1 paper

NM_006293.4

p.P322R

c.965C>G

1 paper

NM_006293.4

p.A321Splc

c.962-2A>G

1 paper

NM_006293.4

p.Q387delFs

c.1161delA