Varaico: Literature-Extracted Genetic Variants

TYRO3

184 papers

RefSeq Summary

The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-...

Pfam Domains

I-setaa 43–135UCSCImmunoglobulin I-set domain

fn3aa 226–316UCSCFibronectin type III domain

fn3aa 324–412UCSCFibronectin type III domain

PK_Tyr_Ser-Thraa 518–786UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

TYRO3 protein tyrosine kinase

HGNC Previous Symbol

RSE

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_006293.4

p.T458M

c.1373C>T

Surrounding Variants

1 paper

NM_006293.4

p.R455W

c.1363C>T

2 papers

NM_006293.4

p.G461Splc

c.1382+2T>C

1 paper

NM_006293.4

p.R452Q

c.1355G>A

1 paper

NM_006293.4

p.R452*

c.1354C>T

2 papers

NM_006293.4

p.Q462fs

c.1384_1385fs

1 paper

NM_006293.4

p.R426R

c.1278C>T

1 paper

NM_006293.4

p.R470Q

c.1409G>A

1 paper

NM_006293.4

p.V475F

c.1423G>T

1 paper

NM_006293.4

p.H476Y

c.1426C>T

1 paper

NM_006293.4

p.R481Q

c.1442G>A

1 paper

NM_006293.4

p.S482insFs

c.1444_1445ins4

4 papers

NM_006293.4

p.E489K

c.1465G>A