Varaico: Literature-Extracted Genetic Variants

TYRO3

184 papers

RefSeq Summary

The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-...

Pfam Domains

I-setaa 43–135UCSCImmunoglobulin I-set domain

fn3aa 226–316UCSCFibronectin type III domain

fn3aa 324–412UCSCFibronectin type III domain

PK_Tyr_Ser-Thraa 518–786UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

TYRO3 protein tyrosine kinase

HGNC Previous Symbol

RSE

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006293.4

p.E489*

c.1465G>T

Surrounding Variants

4 papers

NM_006293.4

p.E489K

c.1465G>A

1 paper

NM_006293.4

p.E489A

c.1466A>C

1 paper

NM_006293.4

p.R490H

c.1469G>A

1 paper

NM_006293.4

p.A493T

c.1477G>A

1 paper

NM_006293.4

p.L495Splc

c.1483+1G>T

1 paper

NM_006293.4

p.L495Splc

c.1483+2T>C

1 paper

NM_006293.4

p.S482insFs

c.1444_1445ins4

1 paper

NM_006293.4

p.R481Q

c.1442G>A

1 paper

NM_006293.4

p.H476Y

c.1426C>T

1 paper

NM_006293.4

p.V475F

c.1423G>T

1 paper

NM_006293.4

p.R470Q

c.1409G>A

2 papers

NM_006293.4

p.Q462fs

c.1384_1385fs