Varaico: Literature-Extracted Genetic Variants

TYRO3

184 papers

RefSeq Summary

The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-...

Pfam Domains

I-setaa 43–135UCSCImmunoglobulin I-set domain

fn3aa 226–316UCSCFibronectin type III domain

fn3aa 324–412UCSCFibronectin type III domain

PK_Tyr_Ser-Thraa 518–786UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

TYRO3 protein tyrosine kinase

HGNC Previous Symbol

RSE

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006293.4

p.D510N

c.1528G>A

Surrounding Variants

1 paper

NM_006293.4

p.V511_L512ins4

c.1531_1535ins12

1 paper

NM_006293.4

p.P514S

c.1540C>T

1 paper

NM_006293.4

p.T519A

c.1555A>G

1 paper

NM_006293.4

p.R522W

c.1564C>T

1 paper

NM_006293.4

p.R522Q

c.1565G>A

1 paper

NM_006293.4

p.S497insFs

c.1491dupC

7 papers

NM_001330264.2

p.L450Splc

c.1349-1G>T

NM_006293.4

p.L495Splc

c.1484-1G>T

1 paper

NM_006293.4

p.G527insFs

c.1579_1580ins4

1 paper

NM_006293.4

p.G527Splc

c.1579+3A>T

1 paper

NM_006293.4

p.L495Splc

c.1483+2T>C

1 paper

NM_006293.4

p.L495Splc

c.1483+1G>T

1 paper

NM_006293.4

p.A493T

c.1477G>A