Varaico: Literature-Extracted Genetic Variants

TYRO3

184 papers

RefSeq Summary

The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-...

Pfam Domains

I-setaa 43–135UCSCImmunoglobulin I-set domain

fn3aa 226–316UCSCFibronectin type III domain

fn3aa 324–412UCSCFibronectin type III domain

PK_Tyr_Ser-Thraa 518–786UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

TYRO3 protein tyrosine kinase

HGNC Previous Symbol

RSE

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_006293.4

p.F674L

c.2022C>A

Surrounding Variants

2 papers

NM_006293.4

p.F674L

c.2022C>G

2 papers

NM_006293.4

p.G675R

c.2023G>A

2 papers

NM_006293.4

p.G675R

c.2023G>C

2 papers

NM_006293.4

p.F674L

c.2020T>C

1 paper

NM_006293.4

p.L676H

c.2027T>A

1 paper

NM_006293.4

p.I680F

c.2038A>T

7 papers

NM_006293.4

p.V669L

c.2005G>C

7 papers

NM_006293.4

p.V669L

c.2005G>T

1 paper

NM_006293.4

p.S682N

c.2045G>A

1 paper

NM_006293.4

p.D666G

c.1997A>G

1 paper

NM_006293.4

p.D666_M667ins6

c.1996_2000ins18

1 paper

NM_006293.4

p.D666_M667ins15

c.1996_2000ins45