Varaico: Literature-Extracted Genetic Variants

TYW1

55 papers

RefSeq Summary

Wybutosine (yW) is a hypermodified guanosine found in phenylalanine tRNA adjacent to the anticodon that stabilizes codon-anticodon interactions in the ribosome. In yeast, the homolog of this gene is e...

Pfam Domains

Flavodoxin_1aa 81–232UCSCFlavodoxin

Radical_SAMaa 410–592UCSCRadical SAM superfamily

Wyosine_formaa 594–657UCSCWyosine base formation

Gene Aliases

HGNC Name

tRNA-yW synthesizing protein 1 homolog

HGNC Previous Symbol

RSAFD1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_018264.4

p.R173K

c.518G>A

Surrounding Variants

2 papers

NM_018264.4

p.Y174D

c.520T>G

1 paper

NM_018264.4

p.A175V

c.524C>T

1 paper

NM_018264.4

p.T167P

c.499A>C

1 paper

NM_018264.4

p.P144S

c.430C>T

1 paper

NM_018264.4

p.V136A

c.407T>C

1 paper

NM_018264.4

p.V133V

c.399C>G

2 papers

NM_018264.4

p.R206C

c.616C>T

1 paper

NM_018264.4

p.D228G

c.683A>G

1 paper

NM_018264.4

p.R230S

c.690A>C

1 paper

NM_018264.4

p.R230S

c.690A>T

2 papers

NM_018264.4

p.K260_C261delFs

c.778_781del4

2 papers

NM_018264.4

p.K260fs

c.778_779fs