Varaico: Literature-Extracted Genetic Variants

TYW1

55 papers

RefSeq Summary

Wybutosine (yW) is a hypermodified guanosine found in phenylalanine tRNA adjacent to the anticodon that stabilizes codon-anticodon interactions in the ribosome. In yeast, the homolog of this gene is e...

Pfam Domains

Flavodoxin_1aa 81–232UCSCFlavodoxin

Radical_SAMaa 410–592UCSCRadical SAM superfamily

Wyosine_formaa 594–657UCSCWyosine base formation

Gene Aliases

HGNC Name

tRNA-yW synthesizing protein 1 homolog

HGNC Previous Symbol

RSAFD1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_018264.4

p.G393A

c.1178G>C

Surrounding Variants

2 papers

NM_018264.4

p.R389Q

c.1166G>A

1 paper

NM_018264.4

p.F399L

c.1195T>C

1 paper

NM_018264.4

p.F399L

c.1197C>A

1 paper

NM_018264.4

p.F399L

c.1197C>G

1 paper

NM_018264.4

p.H405N

c.1213C>A

1 paper

NM_018264.4

p.R406C

c.1216C>T

6 papers

NM_018264.4

p.R425W

c.1273C>T