Varaico: Literature-Extracted Genetic Variants

TYW1B

39 papers

RefSeq Summary

Wybutosine is a hypermodified guanosine found in phenylalanine tRNA. Wybutosine functions to stabilize codon-anticodon interactions during ribosome decoding and therefore supports the maintenance of t...

Pfam Domains

Flavodoxin_1aa 43–186UCSCFlavodoxin

Radical_SAMaa 346–528UCSCRadical SAM superfamily

Wyosine_formaa 530–593UCSCWyosine base formation

Gene Aliases

HGNC Name

tRNA-yW synthesizing protein 1 homolog B

HGNC Alias Symbols

RSAFD2; MGC87315; NCRNA00069; LINC00069

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_001145440.3

p.L372W

c.1115T>G

Surrounding Variants

1 paper

NM_001145440.3

p.L372L

c.1114T>C

1 paper

NM_001145440.3

p.L372delins

c.1114_1115delinsTT

11 papers

NM_001145440.3

p.W373*

c.1118G>A

1 paper

NM_001145440.3

p.L372_W373delins

c.1114_1118delinsCGGTA

10 papers

NM_001145440.3

p.W373*

c.1119G>A