ubiquitin conjugating enzyme E2 L3

UBCH7

ubiquitin-conjugating enzyme E2L 3

Ubiquitin-conjugating enzyme E2 L3

E2 ubiquitin-conjugating enzyme L3

L-UBC

UbcH7

Ubiquitin carrier protein L3

Ubiquitin-conjugating enzyme E2-F1

Ubiquitin-protein ligase L3

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2009].

Varaico: Literature-Extracted Genetic Variants

UBE2L3

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Alias Symbol