Varaico: Literature-Extracted Genetic Variants

Gene:UBN1
Variant:p.L78delFs

UBN1

78 papers

RefSeq Summary

Cellular senescence is a hallmark of tumor suppression and tissue aging. Senescent cells contain domains of heterochromatin, called senescence-associated heterochromatin foci (SAHF), that repress prol...

Pfam Domains

HUNaa 117–168UCSCHPC2 and ubinuclein domain
UBN_ABaa 353–573UCSCUbinuclein conserved middle domain

Gene Aliases

HGNC Name

ubinuclein 1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001079514.3
p.L78delFs
c.233_234delTT
Surrounding Variants
1 paper
NM_001079514.3
p.P80fs
c.238_239fs
1 paper
NM_001079514.3
p.V68E
c.203T>A
1 paper
NM_001079514.3
p.E66K
c.196G>A
1 paper
NM_001079514.3
p.E61K
c.181G>A
1 paper
NM_001079514.3
p.E53K
c.157G>A
1 paper
NM_001079514.3
p.R25L
c.74G>T
1 paper
NM_001079514.3
p.S11C
c.32C>G
1 paper
NM_001079514.3
p.F91L
c.271T>C
1 paper
NM_001079514.3
p.F91L
c.273C>A
1 paper
NM_001079514.3
p.F91L
c.273C>G
1 paper
NM_001079514.3
p.E94K
c.280G>A
1 paper
NM_001079514.3
p.E102Q
c.304G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."