Varaico: Literature-Extracted Genetic Variants

Gene:UBN1
Variant:p.L786M

UBN1

78 papers

RefSeq Summary

Cellular senescence is a hallmark of tumor suppression and tissue aging. Senescent cells contain domains of heterochromatin, called senescence-associated heterochromatin foci (SAHF), that repress prol...

Pfam Domains

HUNaa 117–168UCSCHPC2 and ubinuclein domain
UBN_ABaa 353–573UCSCUbinuclein conserved middle domain

Gene Aliases

HGNC Name

ubinuclein 1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
6 papers
NM_001079514.3
p.L786M
c.2356T>A
Surrounding Variants
1 paper
NM_001079514.3
p.V804L
c.2410G>C
1 paper
NM_001079514.3
p.T811S
c.2431A>T
1 paper
NM_001079514.3
p.T811S
c.2432C>G
1 paper
NM_001079514.3
p.T811I
c.2432C>T
1 paper
NM_001079514.3
p.P755T
c.2263C>A
1 paper
NM_001079514.3
p.E752D
c.2256G>C
1 paper
NM_001079514.3
p.E752D
c.2256G>T
1 paper
NM_001079514.3
p.S749F
c.2246C>T
1 paper
NM_001079514.3
p.A745S
c.2233G>T
1 paper
NM_001079514.3
p.S734L
c.2201C>T
1 paper
NM_001079514.3
p.S840S
c.2520C>T
1 paper
NM_001079514.3
p.P856S
c.2566C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."