ubiquitin C-terminal hydrolase L3

ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)

ubiquitin thiolesterase

Ubiquitin carboxyl-terminal hydrolase isozyme L3

Ubiquitin thioesterase L3

UCH-L3

Ubiquitin carboxyl-terminal hydrolase, family 1

The protein encoded by this gene is a member of the deubiquitinating enzyme family. Members of this family are proteases that catalyze the removal of ubiquitin from polypeptides and are divided into five classes, depending on the mechanism of catalysis. This protein may hydrolyze the ubiquitinyl-N-epsilon amide bond of ubiquitinated proteins to regenerate ubiquitin for another catalytic cycle. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012].

Varaico: Literature-Extracted Genetic Variants

UCHL3

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Name