Varaico: Literature-Extracted Genetic Variants

Gene:UGT1A1
Variant:p.P152L

UGT1A1

1,221 papers

RefSeq Summary

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-solub...

Pfam Domains

UDPGTaa 28–524UCSCUDP-glucoronosyl and UDP-glucosyl transferase

Gene Aliases

HGNC Name

UDP glucuronosyltransferase family 1 member A1

HGNC Previous Symbols

UGT1; GNT1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000463.3
p.P152L
c.455C>T
Surrounding Variants
1 paper
NM_000463.3
p.P152T
c.454C>A
1 paper
NM_000463.3
p.P152S
c.454C>T
1 paper
NM_000463.3
p.F153L
c.457T>C
1 paper
NM_000463.3
p.F153V
c.457T>G
1 paper
NM_000463.3
p.D151A
c.452A>C
2 papers
NM_000463.3
p.D151G
c.452A>G
1 paper
NM_000463.3
p.F153S
c.458T>C
1 paper
NM_000463.3
p.F153L
c.459C>A
1 paper
NM_000463.3
p.F153L
c.459C>G
1 paper
NM_000463.3
p.L154L
c.462T>C
4 papers
NM_000463.3
p.P155T
c.463C>A
1 paper
NM_000463.3
p.L149L
c.447G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."