Varaico: Literature-Extracted Genetic Variants

Gene:UGT1A1
Variant:p.V261A

UGT1A1

1,221 papers

RefSeq Summary

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-solub...

Pfam Domains

UDPGTaa 28–524UCSCUDP-glucoronosyl and UDP-glucosyl transferase

Gene Aliases

HGNC Name

UDP glucuronosyltransferase family 1 member A1

HGNC Previous Symbols

UGT1; GNT1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000463.3
p.V261A
c.782T>C
Surrounding Variants
1 paper
NM_000463.3
p.V261M
c.781G>A
9 papers
NM_000463.3
p.K262R
c.785A>G
1 paper
NM_000463.3
p.F260S
c.779T>C
2 papers
NM_000463.3
p.F260C
c.779T>G
2 papers
NM_000463.3
p.D259E
c.777C>A
1 paper
NM_000463.3
p.D259E
c.777C>G
1 paper
NM_000463.3
p.D263N
c.787G>A
1 paper
NM_000463.3
p.D263H
c.787G>C
1 paper
NM_000463.3
p.D263Y
c.787G>T
2 papers
NM_000463.3
p.D259H
c.775G>C
1 paper
NM_000463.3
p.S258G
c.772A>G
3 papers
NM_000463.3
p.Y264*
c.792C>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."