unc-5 netrin receptor B

UNC5H2

p53RDL1

unc5 (C.elegans homolog) b

unc-5 homolog B (C. elegans)

Netrin receptor UNC5B

Protein unc-5 homolog 2

Protein unc-5 homolog B

p53-regulated receptor for death and life protein 1

This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011].

Varaico: Literature-Extracted Genetic Variants

UNC5B

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Alias Symbols