Varaico: Literature-Extracted Genetic Variants

UNC5C

144 papers

RefSeq Summary

This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins...

Pfam Domains

Unc5_NetrinR_Naa 56–160UCSCNetrin receptor unc-5 N-terminal domain

I-setaa 167–257UCSCImmunoglobulin I-set domain

TSP_1aa 264–313UCSCThrombospondin type 1 domain

TSP_1aa 317–367UCSCThrombospondin type 1 domain

ZU5aa 532–628UCSCZU5 domain

UPAaa 678–817UCSCUPA domain

Gene Aliases

HGNC Name

unc-5 netrin receptor C

HGNC Previous Names

unc5 (C.elegans homolog) c; unc-5 homolog C (C. elegans)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003728.4

p.D747N

c.2239G>A

Surrounding Variants

2 papers

NM_003728.4

p.D747G

c.2240A>G

1 paper

NM_003728.4

p.R742H

c.2225G>A

1 paper

NM_003728.4

p.S737N

c.2210G>A

1 paper

NM_003728.4

p.F734I

c.2200T>A

1 paper

NM_003728.4

p.E727K

c.2179G>A

1 paper

NM_003728.4

p.L726Q

c.2177T>A

1 paper

NM_003728.4

p.M721I

c.2163G>T

1 paper

NM_003728.4

p.M721I

c.2163G>C

1 paper

NM_003728.4

p.M721I

c.2163G>A

6 papers

NM_003728.4

p.M721T

c.2162T>C

1 paper

NM_003728.4

p.C795S

c.2383T>A

1 paper

NM_003728.4

p.C795S

c.2384G>C