Varaico: Literature-Extracted Genetic Variants

UNC5C

144 papers

RefSeq Summary

This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins...

Pfam Domains

Unc5_NetrinR_Naa 56–160UCSCNetrin receptor unc-5 N-terminal domain

I-setaa 167–257UCSCImmunoglobulin I-set domain

TSP_1aa 264–313UCSCThrombospondin type 1 domain

TSP_1aa 317–367UCSCThrombospondin type 1 domain

ZU5aa 532–628UCSCZU5 domain

UPAaa 678–817UCSCUPA domain

Gene Aliases

HGNC Name

unc-5 netrin receptor C

HGNC Previous Names

unc5 (C.elegans homolog) c; unc-5 homolog C (C. elegans)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003728.4

p.A654T

c.1960G>A

Surrounding Variants

1 paper

NM_003728.4

p.A656T

c.1966G>A

2 papers

NM_003728.4

p.A668T

c.2002G>A

1 paper

NM_003728.4

p.K680K

c.2040G>A

2 papers

NM_003728.4

p.P689A

c.2065C>G

1 paper

NM_003728.4

p.L690Q

c.2069T>A

1 paper

NM_003728.4

p.C692F

c.2075G>T

1 paper

NM_003728.4

p.V701F

c.2101G>T

1 paper

NM_003728.4

p.A710S

c.2128G>T

1 paper

NM_003728.4

p.K712N

c.2136G>T

1 paper

NM_003728.4

p.K712N

c.2136G>C

3 papers

NM_003728.4

p.Q630E

c.1888C>G

2 papers

NM_003728.4

p.A628E

c.1883C>A