Varaico: Literature-Extracted Genetic Variants

UNC5C

144 papers

RefSeq Summary

This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins...

Pfam Domains

Unc5_NetrinR_Naa 56–160UCSCNetrin receptor unc-5 N-terminal domain

I-setaa 167–257UCSCImmunoglobulin I-set domain

TSP_1aa 264–313UCSCThrombospondin type 1 domain

TSP_1aa 317–367UCSCThrombospondin type 1 domain

ZU5aa 532–628UCSCZU5 domain

UPAaa 678–817UCSCUPA domain

Gene Aliases

HGNC Name

unc-5 netrin receptor C

HGNC Previous Names

unc5 (C.elegans homolog) c; unc-5 homolog C (C. elegans)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_003728.4

p.Q630E

c.1888C>G

Surrounding Variants

2 papers

NM_003728.4

p.A628E

c.1883C>A

1 paper

NM_003728.4

p.A628delins

c.1882_1883delinsAA

1 paper

NM_003728.4

p.A628T

c.1882G>A

1 paper

NM_003728.4

p.N626D

c.1876A>G

2 papers

NM_003728.4

p.T617I

c.1850C>T

1 paper

NM_003728.4

p.A613S

c.1837G>T

1 paper

NM_003728.4

p.P604S

c.1810C>T

4 papers

NM_003728.4

p.R603C

c.1807C>T

1 paper

NM_003728.4

p.C594Y

c.1781G>A

1 paper

NM_003728.4

p.A654T

c.1960G>A

1 paper

NM_003728.4

p.A656T

c.1966G>A

2 papers

NM_003728.4

p.A668T

c.2002G>A