Varaico: Literature-Extracted Genetic Variants

UNC5C

144 papers

RefSeq Summary

This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins...

Pfam Domains

Unc5_NetrinR_Naa 56–160UCSCNetrin receptor unc-5 N-terminal domain

I-setaa 167–257UCSCImmunoglobulin I-set domain

TSP_1aa 264–313UCSCThrombospondin type 1 domain

TSP_1aa 317–367UCSCThrombospondin type 1 domain

ZU5aa 532–628UCSCZU5 domain

UPAaa 678–817UCSCUPA domain

Gene Aliases

HGNC Name

unc-5 netrin receptor C

HGNC Previous Names

unc5 (C.elegans homolog) c; unc-5 homolog C (C. elegans)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003728.4

p.C332R

c.994T>C

Surrounding Variants

1 paper

NM_003728.4

p.T333P

c.997A>C

1 paper

NM_003728.4

p.H334fs

c.1000_1001fs

1 paper

NM_003728.4

p.R336C

c.1006C>T

1 paper

NM_003728.4

p.R336H

c.1007G>A

1 paper

NM_003728.4

p.C340Y

c.1019G>A

1 paper

NM_003728.4

p.W322*

c.966G>A

1 paper

NM_003728.4

p.W322*

c.965G>A

5 papers

NM_003728.4

p.D353N

c.1057G>A

1 paper

NM_003728.4

p.T311M

c.932C>T

1 paper

NM_003728.4

p.S303T

c.908G>C

1 paper

NM_003728.4

p.R278P

c.833G>C

1 paper

NM_003728.4

p.R275H

c.824G>A