Varaico: Literature-Extracted Genetic Variants

UNC5C

144 papers

RefSeq Summary

This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins...

Pfam Domains

Unc5_NetrinR_Naa 56–160UCSCNetrin receptor unc-5 N-terminal domain

I-setaa 167–257UCSCImmunoglobulin I-set domain

TSP_1aa 264–313UCSCThrombospondin type 1 domain

TSP_1aa 317–367UCSCThrombospondin type 1 domain

ZU5aa 532–628UCSCZU5 domain

UPAaa 678–817UCSCUPA domain

Gene Aliases

HGNC Name

unc-5 netrin receptor C

HGNC Previous Names

unc5 (C.elegans homolog) c; unc-5 homolog C (C. elegans)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003728.4

p.K176N

c.528G>T

Surrounding Variants

1 paper

NM_003728.4

p.K176N

c.528G>C

1 paper

NM_003728.4

p.E177E

c.531A>G

1 paper

NM_003728.4

p.G175E

c.524G>A

1 paper

NM_003728.4

p.E183K

c.547G>A

1 paper

NM_003728.4

p.F169L

c.507T>G

1 paper

NM_003728.4

p.F169L

c.507T>A

1 paper

NM_003728.4

p.F169L

c.505T>C

1 paper

NM_003728.4

p.R166Q

c.497G>A

1 paper

NM_003728.4

p.P190T

c.568C>A

1 paper

NM_003728.4

p.P190fs

c.568_569fs

1 paper

NM_003728.4

p.P191R

c.572C>G

1 paper

NM_003728.4

p.P195S

c.583C>T