ubiquitin specific peptidase 10

UBPO

KIAA0190

ubiquitin specific protease 10

Ubiquitin carboxyl-terminal hydrolase 10

Deubiquitinating enzyme 10

Ubiquitin thioesterase 10

Ubiquitin-specific-processing protease 10

Ubiquitin is a highly conserved protein that is covalently linked to other proteins to regulate their function and degradation. This gene encodes a member of the ubiquitin-specific protease family of cysteine proteases. The enzyme specifically cleaves ubiquitin from ubiquitin-conjugated protein substrates. The protein is found in the nucleus and cytoplasm. It functions as a co-factor of the DNA-bound androgen receptor complex, and is inhibited by a protein in the Ras-GTPase pathway. The human genome contains several pseudogenes similar to this gene. Several transcript variants, some protein-coding and others not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2013].

Varaico: Literature-Extracted Genetic Variants

USP10

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Alias Symbols