Varaico: Literature-Extracted Genetic Variants

USP25

98 papers

RefSeq Summary

Ubiquitin (MIM 191339) is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response. Ubiquitin is released from deg...

Pfam Domains

UBA_8aa 15–61UCSCUBA-like domain

UIMaa 97–113UCSCUbiquitin interaction motif

UCHaa 169–654UCSCUbiquitin carboxyl-terminal hydrolase

Gene Aliases

HGNC Name

ubiquitin specific peptidase 25

HGNC Previous Name

ubiquitin specific protease 25

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001283041.3

p.K99Q

c.295A>C

Surrounding Variants

1 paper

NM_001283041.3

p.K99R

c.296A>G

1 paper

NM_001283041.3

p.L108_S109del1

c.323_325delTGA

1 paper

NM_001283041.3

p.Q127K

c.379C>A

1 paper

NM_001283041.3

p.I129N

c.386T>A