Varaico: Literature-Extracted Genetic Variants

USP25

98 papers

RefSeq Summary

Ubiquitin (MIM 191339) is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response. Ubiquitin is released from deg...

Pfam Domains

UBA_8aa 15–61UCSCUBA-like domain

UIMaa 97–113UCSCUbiquitin interaction motif

UCHaa 169–654UCSCUbiquitin carboxyl-terminal hydrolase

Gene Aliases

HGNC Name

ubiquitin specific peptidase 25

HGNC Previous Name

ubiquitin specific protease 25

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001283041.3

p.L209S

c.626T>C

Surrounding Variants

1 paper

NM_001283041.3

p.L209F

c.627A>C

1 paper

NM_001283041.3

p.L209F

c.627A>T

1 paper

NM_001283041.3

p.S186*

c.557C>A

1 paper

NM_001283041.3

p.S186*

c.557C>G

1 paper

NM_001283041.3

p.R217G

c.649C>G

1 paper

NM_001283041.3

p.R217Q

c.650G>A

1 paper

NM_001283041.3

p.M222V

c.664A>G

1 paper

NM_001283041.3

p.Y227C

c.680A>G

1 paper

NM_001283041.3

p.L228V

c.682C>G

1 paper

NM_001283041.3

p.T235N

c.704C>A

1 paper

NM_001283041.3

p.P242Q

c.725C>A

1 paper

NM_001283041.3

p.V183V

c.549T>C