Varaico: Literature-Extracted Genetic Variants

USP25

98 papers

RefSeq Summary

Ubiquitin (MIM 191339) is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response. Ubiquitin is released from deg...

Pfam Domains

UBA_8aa 15–61UCSCUBA-like domain

UIMaa 97–113UCSCUbiquitin interaction motif

UCHaa 169–654UCSCUbiquitin carboxyl-terminal hydrolase

Gene Aliases

HGNC Name

ubiquitin specific peptidase 25

HGNC Previous Name

ubiquitin specific protease 25

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001283041.3

p.F363C

c.1088T>G

Surrounding Variants

1 paper

NM_001283041.3

p.E365K

c.1093G>A

1 paper

NM_001283041.3

p.E373A

c.1118A>C

1 paper

NM_001283041.3

p.G384*

c.1150G>T

1 paper

NM_001283041.3

p.I389I

c.1167T>C

1 paper

NM_001283041.3

p.H390R

c.1169A>G

1 paper

NM_001283041.3

p.Y454F

c.1361A>T

1 paper

NM_001283041.3

p.P478H

c.1433C>A

1 paper

NM_001283041.3

p.S481Y

c.1442C>A

1 paper

NM_001283041.3

p.S513S

c.1539A>T

1 paper

NM_001283041.3

p.P521A

c.1561C>G

1 paper

NM_001283041.3

p.P521S

c.1561C>T

1 paper

NM_001283041.3

p.F522L

c.1564T>C