Varaico: Literature-Extracted Genetic Variants

USP25

98 papers

RefSeq Summary

Ubiquitin (MIM 191339) is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response. Ubiquitin is released from deg...

Pfam Domains

UBA_8aa 15–61UCSCUBA-like domain

UIMaa 97–113UCSCUbiquitin interaction motif

UCHaa 169–654UCSCUbiquitin carboxyl-terminal hydrolase

Gene Aliases

HGNC Name

ubiquitin specific peptidase 25

HGNC Previous Name

ubiquitin specific protease 25

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001283041.3

p.F522L

c.1566T>A

Surrounding Variants

1 paper

NM_001283041.3

p.F522L

c.1566T>G

1 paper

NM_001283041.3

p.T523A

c.1567A>G

1 paper

NM_001283041.3

p.F522L

c.1564T>C

1 paper

NM_001283041.3

p.P521A

c.1561C>G

1 paper

NM_001283041.3

p.P521S

c.1561C>T

1 paper

NM_001283041.3

p.S525P

c.1573T>C

1 paper

NM_001283041.3

p.S513S

c.1539A>T

2 papers

NM_001283041.3

p.P535L

c.1604C>T

1 paper

NM_001283041.3

p.T541R

c.1622C>G

1 paper

NM_001283041.3

p.E542D

c.1626G>C

1 paper

NM_001283041.3

p.E542D

c.1626G>T

1 paper

NM_001283041.3

p.E549Q

c.1645G>C