Varaico: Literature-Extracted Genetic Variants

USP25

98 papers

RefSeq Summary

Ubiquitin (MIM 191339) is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response. Ubiquitin is released from deg...

Pfam Domains

UBA_8aa 15–61UCSCUBA-like domain

UIMaa 97–113UCSCUbiquitin interaction motif

UCHaa 169–654UCSCUbiquitin carboxyl-terminal hydrolase

Gene Aliases

HGNC Name

ubiquitin specific peptidase 25

HGNC Previous Name

ubiquitin specific protease 25

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001283041.3

p.M819I

c.2457G>T

Surrounding Variants

1 paper

NM_001283041.3

p.M819I

c.2457G>A

1 paper

NM_001283041.3

p.M819I

c.2457G>C

1 paper

NM_001283041.3

p.I827ins1

c.2480_2481insACC

2 papers

NM_001283041.3

p.M829V

c.2485A>G

1 paper

NM_001283041.3

p.A830V

c.2489C>T

1 paper

NM_001283041.3

p.S836C

c.2506A>T

2 papers

NM_001283041.3

p.N791D

c.2371A>G

1 paper

NM_001283041.3

p.E769*

c.2305G>T