Varaico: Literature-Extracted Genetic Variants

Gene:USP4
Variant:p.Q667E

USP4

92 papers

RefSeq Summary

The protein encoded by this gene is a protease that deubiquitinates target proteins such as ADORA2A and TRIM21. The encoded protein shuttles between the nucleus and cytoplasm and is involved in mainta...

Pfam Domains

DUSPaa 31–123UCSCDUSP domain
Ubiquitin_3aa 139–226UCSCUbiquitin-like domain
UCHaa 302–920UCSCUbiquitin carboxyl-terminal hydrolase

Gene Aliases

HGNC Name

ubiquitin specific peptidase 4

HGNC Previous Symbol

UNP

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_003363.4
p.Q667E
c.1999C>G
Surrounding Variants
1 paper
NM_003363.4
p.E682delFs
c.2044delC
1 paper
NM_003363.4
p.E682fs
c.2044_2045fs
1 paper
NM_003363.4
p.F707fs
c.2119_2120fs
1 paper
NM_003363.4
p.D719E
c.2157C>G
1 paper
NM_003363.4
p.D719E
c.2157C>A
2 papers
NM_003363.4
p.A725G
c.2174C>G
1 paper
NM_003363.4
p.N733S
c.2198A>G
1 paper
NM_003363.4
p.S734fs
c.2200_2201fs
2 papers
NM_003363.4
p.R747W
c.2239C>T
1 paper
NM_003363.4
p.Q769K
c.2305C>A
1 paper
NM_003363.4
p.D780Y
c.2338G>T
1 paper
NM_003363.4
p.D780G
c.2339A>G
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