Varaico: Literature-Extracted Genetic Variants

Gene:USP4
Variant:p.W34*

USP4

92 papers

RefSeq Summary

The protein encoded by this gene is a protease that deubiquitinates target proteins such as ADORA2A and TRIM21. The encoded protein shuttles between the nucleus and cytoplasm and is involved in mainta...

Pfam Domains

DUSPaa 31–123UCSCDUSP domain
Ubiquitin_3aa 139–226UCSCUbiquitin-like domain
UCHaa 302–920UCSCUbiquitin carboxyl-terminal hydrolase

Gene Aliases

HGNC Name

ubiquitin specific peptidase 4

HGNC Previous Symbol

UNP

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_003363.4
p.W34*
c.101G>A
Surrounding Variants
1 paper
NM_003363.4
p.W34*
c.102G>A
1 paper
NM_003363.4
p.F42L
c.124T>C
1 paper
NM_003363.4
p.F42C
c.125T>G
1 paper
NM_003363.4
p.F42L
c.126C>G
1 paper
NM_003363.4
p.F42L
c.126C>A
1 paper
NM_003363.4
p.K43R
c.128A>G
1 paper
NM_003363.4
p.G67V
c.200G>T
1 paper
NM_003363.4
p.S72F
c.215C>T
1 paper
NM_003363.4
p.E19Q
c.55G>C
1 paper
NM_003363.4
p.D12Y
c.34G>T
1 paper
NM_003363.4
p.R10Q
c.29G>A
1 paper
NM_003363.4
p.R8H
c.23G>A
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