Varaico: Literature-Extracted Genetic Variants

VCAM1

391 papers

RefSeq Summary

This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell a...

Pfam Domains

I-setaa 25–112UCSCImmunoglobulin I-set domain

C2-setaa 133–221UCSCImmunoglobulin C2-set domain

igaa 232–304UCSCImmunoglobulin domain

I-setaa 313–400UCSCImmunoglobulin I-set domain

C2-setaa 421–509UCSCImmunoglobulin C2-set domain

Ig_3aa 514–583UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

vascular cell adhesion molecule 1

HGNC Alias Symbol

CD106

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001078.4

p.Q212*

c.634C>T

Surrounding Variants

3 papers

NM_001078.4

p.Q212E

c.634C>G

1 paper

NM_001078.4

p.K215R

c.644A>G

1 paper

NM_001078.4

p.E216G

c.647A>G

1 paper

NM_001078.4

p.S206Y

c.617C>A

1 paper

NM_001078.4

p.L217L

c.651G>A

1 paper

NM_001078.4

p.Q218R

c.653A>G

4 papers

NM_001078.4

p.K198N

c.594A>C

4 papers

NM_001078.4

p.K198N

c.594A>T

1 paper

NM_001078.4

p.K198Q

c.592A>C

1 paper

NM_001078.4

p.A197V

c.590C>T

1 paper

NM_001078.4

p.A197S

c.589G>T

1 paper

NM_001078.4

p.P184_V185ins4

c.550_554ins12